产品货号:
Z38293
中文名称:
Histone H2A (acetyl K9)抗体
英文名称:
Anti-Histone H2A (acetyl K9) Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Histone H2A (acetyl K9) Antibody |
指标别名 | Histone H2A type 1-B/E;Histone H2A.2;Histone H2A/a;Histone H2A/m;HIST1H2AB;H2AFM;HIST1H2AE;H2AFA |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC/IF |
基因名称 | H2AC4/H2AC8 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human Histone H2A (acetyl K9) Core component of nucleosome.Nucleosomes wrap and compact DNA into chromatin,limiting DNA accessibility to the cellular machineries which require DNA as a template.Histones thereby play a central role in transcription regulation,DNA repair,DNA replication and chromosomal stability.DNA accessibility is regulated via a complex set of post-translational modifications of histones,also called histone code,and nucleosome remodeling. |
实际分子量 | 14KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Histones are the main constituents of the protein part of chromosomes of eukaryotic cells.They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution.Histones pack the DNA into tight masses of chromatin.Two core histones of each class H2A,H2A,H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome.Histone tails undergo numerous post-translational modifications,which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes.In addition to the genetic code,combinations of the different histone modifications reveal the so-called "histone code".Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. |
Uniprot ID | P04908 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 |
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